{"id":2650,"date":"2019-09-01T15:47:11","date_gmt":"2019-09-01T13:47:11","guid":{"rendered":"https:\/\/www.rcts.fr\/uncategorized\/a-prospective-observational-study-of-conversion-from-immediate-to-prolonged-release-tacrolimus-in-renal-transplant-recipients-in-france-the-opale-study"},"modified":"2020-04-07T15:59:18","modified_gmt":"2020-04-07T13:59:18","slug":"a-prospective-observational-study-of-conversion-from-immediate-to-prolonged-release-tacrolimus-in-renal-transplant-recipients-in-france-the-opale-study","status":"publish","type":"post","link":"https:\/\/www.rcts.fr\/en\/a-prospective-observational-study-of-conversion-from-immediate-to-prolonged-release-tacrolimus-in-renal-transplant-recipients-in-france-the-opale-study\/","title":{"rendered":"A Prospective, Observational Study of Conversion From Immediate- to Prolonged-Release Tacrolimus in Renal Transplant Recipients in France: The OPALE Study"},"content":{"rendered":"

BACKGROUND: Potential benefits of once-daily, prolonged-release tacrolimus over the immediate-release formulation include improved adherence to immunosuppressives post transplantation. An observational study was performed to characterize real-world practice surrounding conversion from immediate- to prolonged-release tacrolimus in kidney transplant recipients.
\nMATERIAL AND METHODS: We performed a prospective, observational study of renal transplant recipients converted from immediate- to prolonged-release tacrolimus capsules. Conversion took place at the baseline visit, within the first 6 months of transplantation (early conversion group) or between 6 and 12 months of transplantation (late conversion group). Data collection was performed at routine follow-up at 6 and 12 months. Endpoints included conversion ratio from immediate- to prolonged-release tacrolimus, reasons for conversion, additional visits due to conversion, safety, and tolerability.<\/p>\n

Val\u00e9rie Moal, Philippe Grimbert, Adrien Beauvais<\/strong>, Laurence Dubel, Yann Le Meur
\nSep 2019 – Annals of Transplantation<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"

BACKGROUND: Potential benefits of once-daily, prolonged-release tacrolimus over the immediate-release formulation include improved adherence to immunosuppressives post transplantation. An observational study was performed to characterize real-world practice surrounding conversion from immediate- to prolonged-release tacrolimus in kidney transplant recipients. MATERIAL AND METHODS: We performed a prospective, observational study of renal transplant recipients converted from immediate- to […]<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false},"categories":[67],"class_list":["post-2650","post","type-post","status-publish","format-standard","hentry","category-transplantation-en"],"acf":[],"yoast_head":"\nA Prospective, Observational Study of Conversion From Immediate- to Prolonged-Release Tacrolimus in Renal Transplant Recipients in France: The OPALE Study - RCTs<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"http:\/\/www.rcts.fr\/en\/a-prospective-observational-study-of-conversion-from-immediate-to-prolonged-release-tacrolimus-in-renal-transplant-recipients-in-france-the-opale-study\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"A Prospective, Observational Study of Conversion From Immediate- to Prolonged-Release Tacrolimus in Renal Transplant Recipients in France: The OPALE Study - RCTs\" \/>\n<meta property=\"og:description\" content=\"BACKGROUND: Potential benefits of once-daily, prolonged-release tacrolimus over the immediate-release formulation include improved adherence to immunosuppressives post transplantation. An observational study was performed to characterize real-world practice surrounding conversion from immediate- to prolonged-release tacrolimus in kidney transplant recipients. 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